Endometriosis Part 40 - What is Gnrh Agonists??
As we mentioned in previous articles during the last stage of the menstrual cycle normally a layer of endometriosis lining in the inside of the uterus is expelled, known as menstruation blood but instead some of the endometriosis tissues grow somewhere in the body causing endometriosis. Endometriosis also reacts to hormonal signals of the monthly menstrual cycle, building up tissue, breaking it, and eliminating it through the menstrual period. In this article, we will discuss what is GnRH(gonadotrophin-releasing hormone) agonists??
I. Definition
GnRH is a hormone released by the hypothalamus which stimulates the pituitary to produce luteinising hormones (LH) and follicle stimulating hormone (FSH) to drive a menstrual cycle.
II. Effectiveness of GnRH
Just likes progesterone-like agonists. GnRH ( gonadotrophin-releasing hormone) have been used in treating endometriosis for more than 20 years. They come in different forms: three-monthly injection, monthly injection, daily injection and nasal spray because of their chemical make up. GnRH are natural hormone blocking medicines, they help to stop the ovulation and create a temporary menopause state.
Study shows that GnRH are effective to reduce symptoms and the size of endometrial implants but unfortunately, symptoms tend to return after stopping treatment in 4 months.
III. Side effects
a) Hot flush, dry vagina caused by temporary of menopause state.
b) Loss of libido caused low level of estrogen and vagina dryness.
c) Loss of bone density caused by low level of estrogen and progesterone.
d) Nutritional deficiency caused by symptoms of menopause state as our body is no longer absorb magnesium and calcium effectively.
I hope this information will help. If you need more information or insurance advices, please follow my article series of the above subject at my home page at:
http://medicaladvisorjournals.blogspot.com
http://lifeanddisabitityinsuranceunderwriter.blogspot.com/
http://endometriosisa.blogspot.com
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